Hypocholesterolemic Properties of Protein Isolate from Cowpeas (Vigna Unguiculata) Sprout in Normal and Diabetic Rats

This research was aimed to determine the potency of hypocholestrolemic properties of
protein isolate from cowpeas sprout through in vivo bioassay by using Sprague Dawley male
rats. The treatments of the research were rat conditions (normal and diabeic rats) and feed
treatments (standard and protein isolate feed). Blood triglyceride, cholesterol total, High Density
Lipoprotein (HDL), and Low Density Lipoprotein (LDL), of rats were analysed on 3th, 6 th, 9 th,
12 th, 15 th days for the treatment and before treatment as control. The result of this research
showed that the blood triglyceride, cholesterol total, LDL decreased and the blood HDL
increased in diabetics rats with protein isolate treatment. The potency of hypocholestrolemic
activity were shown by the ratio of cholesterol total/HDL and LDL/HDL. The ratio of the rats
were normal, exception diabetic rats with standart feed.